Primary immunodeficiency or monogenic inflammatory bowel disease
Gene: IL31RA

IL31RA (interleukin 31 receptor A)
EnsemblGeneIds (GRCh38): ENSG00000164509
EnsemblGeneIds (GRCh37): ENSG00000164509
OMIM: 609510, Gene2Phenotype
IL31RA is in 4 panels

1 review

Louise Daugherty (Genomics England Curator)

Not clearly a primary immunodeficiency. New gene added after review of potential new genes for PID by the Immunology Test Group. This gene was noted as being only theoretical for PID so was rated as Red by the group.
Created: 27 Sep 2019, 2:42 p.m. | Last Modified: 27 Sep 2019, 2:47 p.m.

Panel Version: 1.132

Created: 27 Sep 2019, 2:42 p.m.
Last Modified: 27 Sep 2019, 2:47 p.m.
Panel version: 1.132

Details

Mode of Inheritance

MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown

Sources

NHS GMS
Expert Review Red
London North GLH

Phenotypes

?Amyloidosis, primary localized cutaneous 2, 613955

OMIM

609510

Clinvar variants

Variants in IL31RA

Penetrance

None

Panels with this gene

History Filter Activity

27 Sep 2019, Gel status: 1

Added New Source, Added New Source, Added New Source, Status Update

Louise Daugherty (Genomics England Curator)

Source London North GLH was added to IL31RA. Source Expert Review Red was added to IL31RA. Source NHS GMS was added to IL31RA. Rating Changed from No List (delete) to Red List (low evidence)

27 Sep 2019, Gel status: 0

Created, Added New Source, Set mode of inheritance, Set Phenotypes

Louise Daugherty (Genomics England Curator)

gene: IL31RA was added gene: IL31RA was added to Primary immunodeficiency. Sources: Mode of inheritance for gene: IL31RA was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown Phenotypes for gene: IL31RA were set to ?Amyloidosis, primary localized cutaneous 2, 613955

Primary immunodeficiency or monogenic inflammatory bowel disease Gene: IL31RA