Genes in panel
STRs in panel
Prev Next

Primary immunodeficiency

Gene: PARP1

Red List (low evidence)

PARP1 (poly(ADP-ribose) polymerase 1)
EnsemblGeneIds (GRCh38): ENSG00000143799
EnsemblGeneIds (GRCh37): ENSG00000143799
OMIM: 173870, Gene2Phenotype
PARP1 is in 5 panels

1 review

Sarah Leigh (Genomics England Curator)

Red List (low evidence)

PARP1 Enhances Influenza A Virus Propagation by Facilitating Degradation of Host Type I Interferon Receptor. Therefore, activiation of PARP1 could promote Influenza infection, by interfering with the IFNAR1.
Sources: Literature
Created: 16 Apr 2020, 2:12 p.m.

Mode of inheritance
Unknown

Publications

Details

Mode of Inheritance
Unknown
Sources
  • Literature
OMIM
173870
Clinvar variants
Variants in PARP1
Penetrance
None
Publications
Panels with this gene

History Filter Activity

16 Apr 2020, Gel status: 1

Created, Added New Source, Set mode of inheritance, Set publications

Sarah Leigh (Genomics England Curator)

gene: PARP1 was added gene: PARP1 was added to Primary immunodeficiency. Sources: Literature Mode of inheritance for gene: PARP1 was set to Unknown Publications for gene: PARP1 were set to 31915279 Review for gene: PARP1 was set to RED