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Primary immunodeficiency

Gene: IL31RA

Red List (low evidence)

IL31RA (interleukin 31 receptor A)
EnsemblGeneIds (GRCh38): ENSG00000164509
EnsemblGeneIds (GRCh37): ENSG00000164509
OMIM: 609510, Gene2Phenotype
IL31RA is in 4 panels

1 review

Louise Daugherty (Genomics England Curator)

Not clearly a primary immunodeficiency. New gene added after review of potential new genes for PID by the Immunology Test Group. This gene was noted as being only theoretical for PID so was rated as Red by the group.
Created: 27 Sep 2019, 2:42 p.m. | Last Modified: 27 Sep 2019, 2:47 p.m.
Panel Version: 1.132

Details

Mode of Inheritance
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Sources
  • NHS GMS
  • Expert Review Red
  • London North GLH
Phenotypes
  • ?Amyloidosis, primary localized cutaneous 2, 613955
OMIM
609510
Clinvar variants
Variants in IL31RA
Penetrance
None
Panels with this gene

History Filter Activity

27 Sep 2019, Gel status: 1

Added New Source, Added New Source, Added New Source, Status Update

Louise Daugherty (Genomics England Curator)

Source London North GLH was added to IL31RA. Source Expert Review Red was added to IL31RA. Source NHS GMS was added to IL31RA. Rating Changed from No List (delete) to Red List (low evidence)

27 Sep 2019, Gel status: 0

Created, Added New Source, Set mode of inheritance, Set Phenotypes

Louise Daugherty (Genomics England Curator)

gene: IL31RA was added gene: IL31RA was added to Primary immunodeficiency. Sources: Mode of inheritance for gene: IL31RA was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown Phenotypes for gene: IL31RA were set to ?Amyloidosis, primary localized cutaneous 2, 613955