Childhood solid tumours
Gene: PALB2
As discussed at the Genomics Cancer Panel Workshop, 16th July 2019: the group agreed that there is enough evidence to rate this gene greenCreated: 2 Aug 2019, 11:03 a.m. | Last Modified: 2 Aug 2019, 11:03 a.m.
Panel Version: 1.27
Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal
Phenotypes
Fanconi Anemia
Source NHS GMS was added to PALB2. Added phenotypes Fanconi Anemia for gene: PALB2 Publications for gene PALB2 were changed from to 17200671
Source Expert List was added to PALB2. Rating Changed from Green List (high evidence) to Green List (high evidence)
This gene has been classified as Green List (High Evidence).
Model of inheritance for gene PALB2 was changed to BIALLELIC, autosomal or pseudoautosomal
Model of inheritance for gene PALB2 was changed to BIALLELIC, autosomal or pseudoautosomal
PALB2 was added to Paediatric congenital malformation-dysmorphism-tumour syndromes panel. Sources: UKGTN
Model of inheritance for gene PALB2 was changed to BIALLELIC, autosomal or pseudoautosomal
PALB2 was added to Paediatric congenital malformation-dysmorphism-tumour syndromes panel. Sources: Illumina TruGenome Clinical Sequencing Services
PALB2 was added to Paediatric congenital malformation-dysmorphism-tumour syndromes panel. Sources: Radboud University Medical Center, Nijmegen