Childhood solid tumours
Gene: SLX4
As discussed at the Genomics Cancer Panel Workshop, 16th July 2019: the group agreed that there is enough evidence to rate this gene greenCreated: 2 Aug 2019, 11:03 a.m. | Last Modified: 2 Aug 2019, 11:03 a.m.
Panel Version: 1.27
Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal
Phenotypes
Fanconi anemia, complementation group P, 613951
Source NHS GMS was added to SLX4. Added phenotypes Fanconi anemia, complementation group P, 613951 for gene: SLX4
Source Expert List was added to SLX4. Rating Changed from Green List (high evidence) to Green List (high evidence)
This gene has been classified as Green List (High Evidence).
Model of inheritance for gene SLX4 was changed to BIALLELIC, autosomal or pseudoautosomal
Model of inheritance for gene SLX4 was changed to BIALLELIC, autosomal or pseudoautosomal
SLX4 was added to Paediatric congenital malformation-dysmorphism-tumour syndromes panel. Sources: UKGTN
Model of inheritance for gene SLX4 was changed to BIALLELIC, autosomal or pseudoautosomal
SLX4 was added to Paediatric congenital malformation-dysmorphism-tumour syndromes panel. Sources: Illumina TruGenome Clinical Sequencing Services
SLX4 was added to Paediatric congenital malformation-dysmorphism-tumour syndromes panel. Sources: Radboud University Medical Center, Nijmegen