Childhood solid tumours
Gene: TSC2
As discussed at the Genomics Cancer Panel Workshop, 16th July 2019: the group agreed that there is enough evidence to rate this gene greenCreated: 2 Aug 2019, 11:03 a.m. | Last Modified: 2 Aug 2019, 11:03 a.m.
Panel Version: 1.27
Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Phenotypes
Tuberous sclerosis type 2
Comment on list classification: SEGAs occur in substantial proportion in childhoodCreated: 8 Mar 2016, 12:23 a.m.
Source NHS GMS was added to TSC2. Mode of inheritance for gene TSC2 was changed from MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown Added phenotypes Tuberous sclerosis type 2 for gene: TSC2 Publications for gene TSC2 were changed from 24053982 to 23788249
Source Expert List was added to TSC2. Rating Changed from Green List (high evidence) to Green List (high evidence)
This gene has been classified as Green List (High Evidence).
This gene has been classified as Green List (High Evidence).
TSC2 was added to Paediatric congenital malformation-dysmorphism-tumour syndromes panel. Sources: Expert list
TSC2 was created by richardhywel