Tumour predisposition - childhood onsetGene: XPC
As discussed at the Genomics Cancer Panel Workshop, 16th July 2019: the group agreed that Xeroderma pigmentosum associated genes associated with cancer will be included in this panel and that there is enough evidence to rate this gene green.
Created: 2 Aug 2019, 11:03 a.m. | Last Modified: 2 Aug 2019, 11:03 a.m.
Panel Version: 1.27
Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal
Source Expert Review Green was added to XPC. Source NHS GMS was added to XPC. Mode of inheritance for gene XPC was changed from to BIALLELIC, autosomal or pseudoautosomal Added phenotypes Xeroderma pigmentosum, group C, 278720 for gene: XPC Publications for gene XPC were changed from to 21097776; 22044607; 26975629; 30565713 Rating Changed from Red List (low evidence) to Green List (high evidence)
gene: XPC was added gene: XPC was added to Tumour predisposition - childhood onset. Sources: Expert List Mode of inheritance for gene: XPC was set to