Childhood solid tumours
Gene: PTEN
As discussed at the Genomics Cancer Panel Workshop, 16th July 2019: the group agreed that there is enough evidence to rate this gene greenCreated: 2 Aug 2019, 11:03 a.m. | Last Modified: 2 Aug 2019, 11:03 a.m.
Panel Version: 1.27
Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Phenotypes
Cowden syndrome
Comment when marking as ready: Cowden syndrome could present in this category.Created: 14 Feb 2016, 5:32 p.m.
Source NHS GMS was added to PTEN. Mode of inheritance for gene PTEN was changed from MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown Added phenotypes Cowden syndrome for gene: PTEN Publications for gene PTEN were changed from to 4635800
Source Expert List was added to PTEN. Rating Changed from Green List (high evidence) to Green List (high evidence)
This gene has been classified as Green List (High Evidence).
Mode of inheritance for PTEN was changed to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
PTEN was added to Paediatric congenital malformation-dysmorphism-tumour syndromes panel. Sources: Expert list
PTEN was added to Paediatric congenital malformation-dysmorphism-tumour syndromes panel. Sources: UKGTN
PTEN was added to Paediatric congenital malformation-dysmorphism-tumour syndromes panel. Sources: Emory Genetics Laboratory
PTEN was added to Paediatric congenital malformation-dysmorphism-tumour syndromes panel. Sources: Radboud University Medical Center, Nijmegen