Childhood solid tumours
Gene: APC
As discussed at the Genomics Cancer Panel Workshop, 16th July 2019: the group agreed that there is enough evidence to rate this gene green.Created: 2 Aug 2019, 11:03 a.m. | Last Modified: 2 Aug 2019, 11:03 a.m.
Panel Version: 1.27
Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Phenotypes
Familial Adenomatous Polyposis
Comment on list classification: Associated with hepatoblastomaCreated: 7 Mar 2016, 11:37 p.m.
Source NHS GMS was added to APC. Mode of inheritance for gene APC was changed from MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown Added phenotypes Familial Adenomatous Polyposis for gene: APC Publications for gene APC were changed from 1658283 to 23788249
Source Expert List was added to APC. Rating Changed from Green List (high evidence) to Green List (high evidence)
This gene has been classified as Green List (High Evidence).
This gene has been classified as Green List (High Evidence).
APC was added to Paediatric congenital malformation-dysmorphism-tumour syndromes panel. Sources: Expert list
APC was created by Reviewer_03