Childhood solid tumours
Gene: SMARCB1
As discussed at the Genomics Cancer Panel Workshop, 16th July 2019: the group agreed that there is enough evidence to rate this gene greenCreated: 2 Aug 2019, 11:03 a.m. | Last Modified: 2 Aug 2019, 11:03 a.m.
Panel Version: 1.27
Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Phenotypes
Atypical rhabdoid tumor predisposition
Comment on list classification: Rhabdoid tumour predispositionCreated: 7 Mar 2016, 11:52 p.m.
Source NHS GMS was added to SMARCB1. Mode of inheritance for gene SMARCB1 was changed from MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown Added phenotypes Atypical rhabdoid tumor predisposition for gene: SMARCB1 Publications for gene SMARCB1 were changed from 10521299 to 12016529
Source Expert List was added to SMARCB1. Rating Changed from Green List (high evidence) to Green List (high evidence)
This gene has been classified as Green List (High Evidence).
This gene has been classified as Green List (High Evidence).
SMARCB1 was added to Paediatric congenital malformation-dysmorphism-tumour syndromes panel. Sources: Expert list
SMARCB1 was created by Reviewer_03