Childhood solid tumours
Gene: TRIM37
TRIM37 (tripartite motif containing 37)
EnsemblGeneIds (GRCh38): ENSG00000108395
EnsemblGeneIds (GRCh37): ENSG00000108395
OMIM: 605073, Gene2Phenotype
TRIM37 is in 13 panels
EnsemblGeneIds (GRCh38): ENSG00000108395
EnsemblGeneIds (GRCh37): ENSG00000108395
OMIM: 605073, Gene2Phenotype
TRIM37 is in 13 panels
3 reviews
Ivone Leong (Genomics England Curator)
As discussed at the Genomics Cancer Panel Workshop, 16th July 2019: the group agreed that there is enough evidence to rate this gene greenCreated: 2 Aug 2019, 11:03 a.m. | Last Modified: 2 Aug 2019, 11:03 a.m.
Panel Version: 1.27
Lara Hawkes (Genomics England)
Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal
Phenotypes
253250
Richard Scott (Genomics England Curator)
Comment on list classification: Mulibrey nanism causes growth retardation and predisposition to Wilms tumourCreated: 7 Mar 2016, 11:53 p.m.
Details
- Mode of Inheritance
- BIALLELIC, autosomal or pseudoautosomal
- Sources
-
- NHS GMS
- Expert List
- Expert Review Green
- Phenotypes
-
- Mulibrey nanism 253250
- 253250
- OMIM
- 605073
- Clinvar variants
- Variants in TRIM37
- Penetrance
- Complete
- Publications
- Panels with this gene
-
- Fetal anomalies
- Clefting
- Monogenic short stature
- Undiagnosed metabolic disorders
- Osteogenesis imperfecta
- Childhood solid tumours cancer susceptibility
- Intellectual disability
- Childhood onset dystonia, chorea or related movement disorder
- Likely inborn error of metabolism
- Peroxisomal disorders
- Childhood solid tumours
- DDG2P
- IUGR and IGF abnormalities
History Filter Activity
2 Aug 2019, Gel status: 3
Added New Source, Set Phenotypes
Ivone Leong (Genomics England Curator)Source NHS GMS was added to TRIM37. Added phenotypes Mulibrey nanism 253250 for gene: TRIM37
30 Jan 2019, Gel status: 3
Added New Source, Status Update
Ivone Leong (Genomics England Curator)Source Expert List was added to TRIM37. Rating Changed from Green List (high evidence) to Green List (high evidence)
7 Mar 2016, Gel status: 4
Gene classified by Genomics England curator
Richard Scott (Genomics England Curator)This gene has been classified as Green List (High Evidence).
7 Mar 2016, Gel status: 4
Gene classified by Genomics England curator
Richard Scott (Genomics England Curator)This gene has been classified as Green List (High Evidence).
7 Mar 2016, Gel status: 0
Created
Richard Scott (North Thames GMC/UCL)TRIM37 was created by Reviewer_03
7 Mar 2016, Gel status: 0
Added New Source
Richard Scott (North Thames GMC/UCL)TRIM37 was added to Paediatric congenital malformation-dysmorphism-tumour syndromes panel. Sources: Expert list