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Intellectual disability

Gene: DCHS2

Red List (low evidence)

DCHS2 (dachsous cadherin-related 2)
EnsemblGeneIds (GRCh38): ENSG00000197410
EnsemblGeneIds (GRCh37): ENSG00000197410
OMIM: 612486, Gene2Phenotype
DCHS2 is in 1 panel

3 reviews

Caroline Wright (Sanger)

Red List (low evidence)

Ellen McDonagh (Genomics England Curator)

Red List (low evidence)

Candidate gene for ID in PMID: 26350204. Several association studies for Alzheimer's disease and age of onset. Not found associated with disease in OMIM or Gene2Phenotype.
Created: 27 Oct 2017, 2:46 p.m.

Publications

Lu Raymond (university of cambridge )

Red List (low evidence)

Details

Sources
  • Expert Review Red
OMIM
612486
Clinvar variants
Variants in DCHS2
Penetrance
Complete
Publications
Panels with this gene

History Filter Activity

12 Mar 2018, Gel status: 1

Panel promoted to version 2.0

Ellen McDonagh (Genomics England Curator)

12.03.2018: Due to major updates completed (Phase 1, 2 and 3), this panel was promoted to Version 2 in order to reflect the major updates since November 2017 which have resulted in reviews for 836 genes added by Genomics England Curators and the Clinical Team, 130 new Green genes added to the interpretation pipeline (from 751 to 881 Green genes), and the gene total has increased from 1879 to 1927.

29 Nov 2017, Gel status: 1

Set publications

Ellen McDonagh (Genomics England Curator)

Publications for gene DCHS2 was set to ['22005931', '26126179', '26876984', '26350204']

13 Nov 2015, Gel status: 1

gel status update

GEL ()

The Gel status was updated for this whole panel

13 Nov 2015, Gel status: 2

gel status update

GEL ()

The Gel status was updated for this whole panel

13 Nov 2015, Gel status: 0

Added New Source

Ellen McDonagh (Genomics England Curator)

DCHS2 was added to Intellectual disabilitypanel. Sources: Expert Review Red

13 Nov 2015, Gel status: 0

Created

Ellen McDonagh (Genomics England Curator)

DCHS2 was created by ellenmcdonagh