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Intellectual disability

Gene: TECR

Red List (low evidence)

TECR (trans-2,3-enoyl-CoA reductase)
EnsemblGeneIds (GRCh38): ENSG00000099797
EnsemblGeneIds (GRCh37): ENSG00000099797
OMIM: 610057, Gene2Phenotype
TECR is in 1 panel

3 reviews

Caroline Wright (Sanger)

Red List (low evidence)

Rebecca Foulger (Genomics England curator)

Red List (low evidence)

ID link but only 1 variant reported- probable Founder variant specific to Hutterite population (PMID:21212097).
Created: 31 Oct 2017, 9:24 a.m.

Phenotypes
non-syndromic mental retardation

Publications

Lu Raymond (university of cambridge )

Red List (low evidence)

Details

Sources
  • Expert Review Red
  • Radboud University Medical Center, Nijmegen
Phenotypes
  • non-syndromic mental retardation
Tags
founder-effect
OMIM
610057
Clinvar variants
Variants in TECR
Penetrance
Complete
Publications
Panels with this gene

History Filter Activity

29 Sep 2018, Gel status: 1

Added New Source

Louise Daugherty (Genomics England Curator)

Source Victorian Clinical Genetics Services was added to TECR.

12 Mar 2018, Gel status: 1

Panel promoted to version 2.0

Ellen McDonagh (Genomics England Curator)

12.03.2018: Due to major updates completed (Phase 1, 2 and 3), this panel was promoted to Version 2 in order to reflect the major updates since November 2017 which have resulted in reviews for 836 genes added by Genomics England Curators and the Clinical Team, 130 new Green genes added to the interpretation pipeline (from 751 to 881 Green genes), and the gene total has increased from 1879 to 1927.

29 Nov 2017, Gel status: 1

Set publications

Ellen McDonagh (Genomics England Curator)

Publications for gene TECR was set to ['21212097']

13 Nov 2015, Gel status: 1

gel status update

GEL ()

The Gel status was updated for this whole panel

13 Nov 2015, Gel status: 2

gel status update

GEL ()

The Gel status was updated for this whole panel

13 Nov 2015, Gel status: 1

Added New Source

Ellen McDonagh (Genomics England Curator)

TECR was added to Intellectual disabilitypanel. Source: Expert Review Red

24 Jun 2015, Gel status: 1

Added New Source

Ellen McDonagh (Genomics England Curator)

TECR was added to Intellectual disabilitypanel. Sources: Radboud University Medical Center, Nijmegen