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Intellectual disability

Gene: KIF26B

Red List (low evidence)

KIF26B (kinesin family member 26B)
EnsemblGeneIds (GRCh38): ENSG00000162849
EnsemblGeneIds (GRCh37): ENSG00000162849
OMIM: 614026, Gene2Phenotype
KIF26B is in 1 panel

3 reviews

Olivia Niblock (Genomics England Curator)

Red List (low evidence)

There is one paper (28328126) describing one patient with a deletion covering KIF26B and several other genes. The main focus of the paper is on microcephaly, however, the patient is noted to have some developmental delay.
Created: 13 Dec 2017, 10:16 p.m.

Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown

Publications

Caroline Wright (Sanger)

Red List (low evidence)

Lu Raymond (university of cambridge )

Red List (low evidence)

Details

Mode of Inheritance
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Sources
  • Expert Review Red
OMIM
614026
Clinvar variants
Variants in KIF26B
Penetrance
Complete
Publications
Panels with this gene

History Filter Activity

12 Mar 2018, Gel status: 1

Panel promoted to version 2.0

Ellen McDonagh (Genomics England Curator)

12.03.2018: Due to major updates completed (Phase 1, 2 and 3), this panel was promoted to Version 2 in order to reflect the major updates since November 2017 which have resulted in reviews for 836 genes added by Genomics England Curators and the Clinical Team, 130 new Green genes added to the interpretation pipeline (from 751 to 881 Green genes), and the gene total has increased from 1879 to 1927.

5 Jan 2018, Gel status: 1

Set mode of inheritance, Set publications

Ellen McDonagh (Genomics England Curator)

Model of inheritance for gene KIF26B was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown Publications for gene KIF26B was set to ['29053796']

13 Nov 2015, Gel status: 1

gel status update

GEL ()

The Gel status was updated for this whole panel

13 Nov 2015, Gel status: 2

gel status update

GEL ()

The Gel status was updated for this whole panel

13 Nov 2015, Gel status: 0

Created

Ellen McDonagh (Genomics England Curator)

KIF26B was created by ellenmcdonagh

13 Nov 2015, Gel status: 0

Added New Source

Ellen McDonagh (Genomics England Curator)

KIF26B was added to Intellectual disabilitypanel. Sources: Expert Review Red