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COVID-19 research

Gene: DMBT1

Red List (low evidence)
DMBT1 (deleted in malignant brain tumors 1)
EnsemblGeneIds (GRCh38): ENSG00000187908
EnsemblGeneIds (GRCh37): ENSG00000187908
OMIM: 601969, Gene2Phenotype
DMBT1 is in 1 panel

1 review

Eleanor Williams (Genomics England Curator)

Red List (low evidence)

Preprint - https://www.biorxiv.org/content/10.1101/2020.04.16.045617v1 - Han et al
Found using single cell transcriptomics that DMBT1 (a viral binding scavenger) was highly expressed in alveolar type II cells relative to other lung epithelial subsets and its expression positively correlated with ACE2.
Sources: Literature
Created: 23 Apr 2020, 4:29 a.m.

Mode of inheritance
Unknown

Created: 23 Apr 2020, 4:29 a.m.

Panel version: 0.140

Details

Mode of Inheritance
Unknown
Sources
  • Literature
OMIM
601969
Clinvar variants
Variants in DMBT1
Penetrance
None
Panels with this gene

History Filter Activity

23 Apr 2020, Gel status: 1

Created, Added New Source, Set mode of inheritance

Eleanor Williams (Genomics England Curator)

gene: DMBT1 was added gene: DMBT1 was added to Viral susceptibility. Sources: Literature Mode of inheritance for gene: DMBT1 was set to Unknown Review for gene: DMBT1 was set to RED