COVID-19 research
Gene: SAMD3

SAMD3 (sterile alpha motif domain containing 3)
EnsemblGeneIds (GRCh38): ENSG00000164483
EnsemblGeneIds (GRCh37): ENSG00000164483
SAMD3 is in 2 panels

1 review

Louise Daugherty (Genomics England Curator)

Red List (low evidence)

New gene added after review of potential new genes for PID by the Immunology Test Group. This gene was noted as being only theoretical for PID so was rated as Red by the group.
Created: 27 Sep 2019, 2:53 p.m. | Last Modified: 27 Sep 2019, 2:53 p.m.

Panel Version: 1.132

Created: 27 Sep 2019, 2:53 p.m.
Last Modified: 27 Sep 2019, 2:53 p.m.
Panel version: Imported from Primary immunodeficiency panel version 1.132

Details

Mode of Inheritance

MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown

Sources

London North GLH
NHS GMS
Expert Review Red
NHS GMS
Expert Review Red
London North GLH

Phenotypes

HLH, abnormal GRA

Clinvar variants

Variants in SAMD3

Penetrance

None

Panels with this gene

History Filter Activity

1 Apr 2020, Gel status: 1

Created, Added New Source, Set mode of inheritance, Set Phenotypes

Ellen McDonagh (Genomics England Curator)

gene: SAMD3 was added gene: SAMD3 was added to Viral susceptibility. Sources: Expert Review Red,NHS GMS,London North GLH Mode of inheritance for gene: SAMD3 was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown Phenotypes for gene: SAMD3 were set to HLH, abnormal GRA

COVID-19 research Gene: SAMD3