COVID-19 research
Gene: LYZ

LYZ (lysozyme)
EnsemblGeneIds (GRCh38): ENSG00000090382
EnsemblGeneIds (GRCh37): ENSG00000090382
OMIM: 153450, Gene2Phenotype
LYZ is in 4 panels

2 reviews

Sophie Hambleton (Newcastle University)

Red List (low evidence)

Agree red rating
Created: 23 Oct 2019, 7:08 a.m. | Last Modified: 23 Oct 2019, 7:08 a.m.

Panel Version: 1.132

Created: 23 Oct 2019, 7:08 a.m.
Last Modified: 23 Oct 2019, 7:08 a.m.
Panel version: Imported from Primary immunodeficiency panel version 1.132

Louise Daugherty (Genomics England Curator)

Red List (low evidence)

More relevant to Amyloidosis panel: already green there (https://panelapp.genomicsengland.co.uk/panels/502/) New gene added after review of potential new genes for PID by the Immunology Test Group. This gene was noted as being only theoretical for PID so was rated as Red by the group.
Created: 27 Sep 2019, 2:46 p.m. | Last Modified: 27 Sep 2019, 2:46 p.m.

Panel Version: 1.132

Created: 27 Sep 2019, 2:46 p.m.
Last Modified: 27 Sep 2019, 2:46 p.m.
Panel version: Imported from Primary immunodeficiency panel version 1.132

Details

Mode of Inheritance

MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown

Sources

London North GLH
NHS GMS
Expert Review Red
NHS GMS
Expert Review Red
London North GLH

Phenotypes

Amyloidosis, renal, 105200

OMIM

153450

Clinvar variants

Variants in LYZ

Penetrance

None

Panels with this gene

History Filter Activity

1 Apr 2020, Gel status: 1

Created, Added New Source, Set mode of inheritance, Set Phenotypes

Ellen McDonagh (Genomics England Curator)

gene: LYZ was added gene: LYZ was added to Viral susceptibility. Sources: Expert Review Red,NHS GMS,London North GLH Mode of inheritance for gene: LYZ was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown Phenotypes for gene: LYZ were set to Amyloidosis, renal, 105200

COVID-19 research Gene: LYZ